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SCD DamageSCD ChallengesSCD ChallengesSymptoms & ComplicationsSCD in NumbersLiving With SCDResourcesContact Us
SCD damageThe pathophysiology of SCD drives complications and may lead to premature mortality.1,2Find out whyLoadingThe burdens of SCD on patientsThe psychological, physical, and social effects of SCD may take a toll on patients.3See howLoadingHelpful resource directories and fact sheetsThere are resources to help you support your patients on their SCD journey.Explore resourcesLoadingSee the impact that a mutation in HBB and polymerizartion of HbS have on RBC functionWatch videoLoadingA medical expert discusses SCDListen to an expert discuss the impact of SCD on patients and describe some of the underlying pathophysiology of SCD.Watch the presentationLoading SIGN UP FOR SCD INSIGHTSStay informed about SCD. Sign up LoadingReferences:Buchanan G, Vichinsky E, Krishnamurti L, Shenoy S. Severe sickle cell disease—pathophysiology and therapy. Biol Blood Marrow Transplant. 2010;16(1 suppl):S64-S67. Payne AB, Mehal JM, Chapman C, et al. Trends in sickle cell disease-related mortality in the United States, 1979 to 2017. Ann Emerg Med. 2020;76(3S):S28-S36.Kavanagh PL, Fasipe TA, Wun T. Sickle cell disease: a review. JAMA. 2022;328(1):57-68.References

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